Endocrine Abstracts

Phaeochromocytoma is a rare adrenal tumour and patients usually present with palpitations, headaches, labile blood pressure and uncontrolled hypertension. Diabetes mellitus can occasionally be the presenting feature of pheochromocytoma due to catecholamine induced hyperglycaemia. We report a patient who presented with headaches and dizziness to the emergency department who was diagnosed with Type 1 diabetes incidentally following a random venous glucose of 41.6 mmol/l, capilla...

Background: Type 1 diabetes mellitus is an autoimmune disorder caused by the destruction of the pancreatic beta cells which produce insulin. People with type 1 diabetes usually require at least 3-5 years to develop microvascular complications in comparison to those with type 2 diabetes, who may develop such complications even before the diagnosis of diabetes due to its insidious onset and the delay in diagnosis. We discuss a patient who initially presented with proliferative d...

Key words- Cushing’ Disease, Aortic DissectionBackground: Cushing’s syndrome is a rare endocrine disorder. It is frequently presented with obesity, type 2 diabetes, or hypertension with an increased cardiovascular risk. The association of Cushing’s syndrome with aortic dissection is rare. We report a young man who presented with hypertensive emergency and aortic dissection. He was later found to have Cushing’s disease...

Background: Haematological side effects of Carbimazole including aplastic anaemia, thrombocytopenia and agranulocytosis are widely reported, but haemolytic anaemia is a rare occurrence. In such situations, the management options available for treating overactive thyroid disease will be limited, especially in frail elderly individuals. We report a case of Carbimazole induced haemolytic anaemia successfully treated with steroids and omitting the medication.<...

Background: Amiodarone induced thyroid dysfunction can be either thyrotoxicosis (AIT) or hypothyroidism (AIH). AIT is classified as Type 1 and Type 2. Type 1 occurs in patients with underlying thyroid pathology and Type 2 AIT is a destructive thyroiditis. We describe a patient with severe Type 2 AIT with a protracted course.>Case History: A 40 year old male with Atrial Fibrillation, Obesity and Obstructive Sleep Apnoea h...

Background: Sarcoidosis is an immune-mediated condition characterized by the presence of non-caseating granulomas, primarily impacting the respiratory system, lymphatic system and heart. The involvement of the central nervous system, especially hypothalamic- pituitary involvement is a rare occurrence. We report a patient initially presenting with Cranial Diabetes Insipidus who was later diagnosed to have sarcoidosis.Case presentation: A-67-year old male ...

Background: Haematological side effects of Carbimazole such as aplastic anaemia, thrombocytopenia and agranulocytosis are widely reported. However, Carbimazole induced haemolytic anaemia is rare. Proplythiouracil is known to cause leucopenia, agranulocytosis, bone marrow hypoplasia and pancytopenia. Nevertheless, Propylthiouracil associated haemolytic anemia is rarely reported. In such situations, the options for managing Hyperthyroidism are limited, especially in frail elderl...